منابع مشابه
Drug-Induced Cardiomyopathies
Heart failure represents one of most important causes of death in Western countries. Its high mortality originates in part from severe complications like cardiac contractile dysfunction and/or sudden cardiac death caused by ventricular arrhythmias (Shin et al. 2007). Unfortunately, significant portion of heart failure stems from use (and misuse) of several drugs and medications. Indeed, the car...
متن کاملSERIOUS ARRHYTHMIA INDUCED BY TERFENADINE-ERYTHROMYCIN INTERACTIONS
Since the introduction of our local manufacturing of terfenadine, we have observed and expressed our concern about a small but increasing number of serious ventricular arrhythmias associated with the use of this non sedating antihistamine. In January 1997 a case of torsade de pointes ventricular tachycardia was detected in a previously healthy woman taking terfenadine with erythromycin. El...
متن کاملAconitine-induced cardiac arrhythmia.
Renewed interest in the pharmacological action of aconitine has followed the work of Sherf (1947), Prinzmetal et al. (1950 and 1951), and Brown and Acheson (1952). Its use in experimental medicine produces stimulus formation in the dog's heart with auricular tachycardia and in certain circumstances ventricular tachycardia and fibrillation: it has become a useful tool in the hands of the researc...
متن کاملEffect of gallic acid on electrophysiological properties and ventricular arrhythmia following chemical-induced arrhythmia in rat
Objective(s): Ventricular arrhythmias including ventricular tachycardia (VT) and ventricular fibrillation (VF) are the most important causes of mortality rate. Gallic acid (GA) has beneficial effects on cardiovascular diseases. The aim of this study was to evaluate the effects of GA on electrophysiological parameters such as QRS complex, heart rate (HR), PR interval pa...
متن کاملDrug-induced arrhythmia: pharmacogenomic prescribing?
Drug-induced Torsades de Pointes is a rare, unpredictable, and life-threatening serious adverse event. It can be caused by both cardiac and non-cardiac drugs and has become a major issue in novel drug development and for the regulatory authorities. This review describes the problem, predisposing factors, and the underlying genetic predisposition as it is understood currently. The future potenti...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2015
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2015.08.038